产品详情
产品名称Actin,Smooth Muscle Antibody
来源种属Mouse
克隆性Monoclonal
克隆号IHC506
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Actin is part of the cytoskeletal system of all cell types. Smooth Muscle Actin is found in myofibroblasts and myoepithelium, but not in cardiac and skeletal muscles. Labelling of smooth muscle actin in concert with muscle specific actin staining can allow for differentiation between rhabdomyosarcoma and leiomyosarcoma, as Muscle specific actin is found in rhabdomyoblasts, while smooth muscle actin is found in leiomyosarcomas.
背景文献
Cooke PH. J Cell Biol. 1976; 68:539-556.
Gown AM, et al. J Cell Biol. 1985; 100:807- 813.
Lazarides E. J Histochem Cytochem. 1975; 223:507-528.