产品名称Quizartinib (AC220)
简述Inhibitors
纯化99.42%
生物活性Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 3.
基因/蛋白名称FLT inhibitor
CAS号950769-58-1
计算分子量560.67
配方C29H32N6O4S
保存3 years -20˚C powder;2 years -80˚C in solvent;