产品详情
产品名称Quetiapine Fumarate
简述Inhibitors
纯化99.57%
生物活性Quetiapine Fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar Ⅱ depression, bipolar I depression.
基因/蛋白名称5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor antagonist
CAS号111974-72-2
计算分子量883.09
配方C46H54N6O8S2
保存3 years -20˚C powder;2 years -80˚C in solvent;
产品描述
Research Area:Nervous system
SMILES:C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=C/C(=O)O)\C(=O)O
Pathways:Neuroscience; GPCR/G Protein
Receptor:HT; Adrenergic Receptor; Dopamine
Boling pt:
Melting pt:
Solubility:DMSO: 36 mg/mL (40.76 mM)
Appearance:WhitePowder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Nemeroff CB, et al. J Clin Psychiatry, 2002, 63 Suppl 13, 5-11.