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位置: 首页 > 磷酸化抗体 > Bcr (Phospho-Tyr360) Antibody

Bcr (Phospho-Tyr360) Antibody#11972

Bcr (Phospho-Tyr360) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Bcr (Phospho-Tyr360) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 360.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 360 (T-T-Y(p)-R-M) derived from Human Bcr.

基因/蛋白名称Bcr

修饰Phospho

别名BCR; BCR protein; BCR1; Breakpoint cluster region protein;

数据库入口号Swiss-Prot#: P11274;
NCBI Gene#: 613;
NCBI Protein#: NP_004318.3

UniprotP11274

实际分子量142kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Western blotting: 1:500~1:1000
Western blot analysis of extracts from COS7 tissue using Bcr (Phospho-Tyr360) antibody #11972.The lane on the right is treated with the antigen-specific peptide.
背景

GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Perazzona B, et al. (2008) Oncogene 27, 2208-14. Sun T, Campbell M, Gordon W, Arlinghaus RB (2001) Biopolymers 60, 61-75 . Wu Y, Liu J, Arlinghaus RB (1998)Oncogene 16, 141-6.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

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