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位置: 首页 > 磷酸化抗体 > Calmodulin (Phospho-Thr79/Ser81) Antibody

Calmodulin (Phospho-Thr79/Ser81) Antibody#11978

Calmodulin (Phospho-Thr79/Ser81) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Calmodulin (Phospho-Thr79/Ser81) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of Calmodulin only when phosphorylated at threonine 79/serine 81.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of threonine79/serine81(K-D-T(p)-D-S(p)-E-E) derived from Human Calmodulin .

基因/蛋白名称Calmodulin

修饰Phospho

别名CALM; CALM1; CALM2; CALM3; CAM

数据库入口号Swiss-Prot#: P62158;
NCBI Gene#: 808;
NCBI Protein#: NP_005175.2

UniprotP62158

实际分子量17kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HeLa tissue using Calmodulin (Phospho-Thr79/Ser81) antibody #11978.The lane on the right is treated with the antigen-specific peptide.
背景

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.

Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76
Arrigoni G, et al. (2004) Biochemistry 43, 12788-98
Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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