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位置: 首页 > 磷酸化抗体 > Retinoblastoma (Phospho-Ser608) Antibody

Retinoblastoma (Phospho-Ser608) Antibody#11720

Retinoblastoma (Phospho-Ser608) Antibody
Retinoblastoma (Phospho-Ser608) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Retinoblastoma (Phospho-Ser608) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB IHC

种属反应性Hu Ms

特异性The antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma.

基因/蛋白名称Retinoblastoma

修饰Phospho

别名P105-RB; PP105; PP110; RB1;

数据库入口号Swiss-Prot#: P06400;
NCBI Gene#: 5925;
NCBI Protein#: NP_000312.2.

UniprotP06400

实际分子量110kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Western blot analysis of extracts from JK cells (Lane 2), using Retinoblastoma (Phospho-Ser608) Antibody #11720. The lane on the left is treated with antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using Retinoblastoma (Phospho-Ser608) antibody #11720 (left)or the same antibody preincubated with blocking peptide (right).
背景

Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.

Lee W.-H., Nature 329:642-645(1987).
Lee W.-H., Science 235:1394-1399(1987).
Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).

如果您使用该产品11720发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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