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位置: 首页 > 磷酸化抗体 > OSR1 (Phospho-Thr185) Antibody

OSR1 (Phospho-Thr185) Antibody#11746

OSR1 (Phospho-Thr185) Antibody
OSR1 (Phospho-Thr185) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称OSR1 (Phospho-Thr185) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB IHC

种属反应性Hu

特异性The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine 185.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1.

基因/蛋白名称OSR1

修饰Phospho

别名OXSR1; kinase OSR1; Oxidative-stress responsive 1;

数据库入口号Swiss-Prot#: O95747;
NCBI Gene#: 9943;
NCBI Protein#: NP_005100.1.

UniprotO95747

实际分子量65kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Western blot analysis of extracts from HepG2 cells treated with serum using OSR1 (Phospho-Thr185) Antibody #11746.The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using OSR1 (Phospho-Thr185) antibody #11746 (left)or the same antibody preincubated with blocking peptide (right).
背景

Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress

Tamari M., J. Hum. Genet. 44:116-120(1999).
Kikuno R., DNA Res. 6-197-205(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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