免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 磷酸化抗体 > Trk B (Phospho-Tyr706/Tyr707) Antibody

Trk B (Phospho-Tyr706/Tyr707) Antibody#11758

Trk B (Phospho-Tyr706/Tyr707) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Trk B (Phospho-Tyr706/Tyr707) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu

特异性The antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 706 and tyrosine 707.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y(p)-Y(p)-R-V)derived from Human Trk B.

基因/蛋白名称Trk B

修饰Phospho

别名Trk-B; NTRK2; GP145-TrkB;

数据库入口号Swiss-Prot#: Q16620;
NCBI Gene#: 4915;
NCBI Protein#: NP_001018074.1.

UniprotQ16620

实际分子量91kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Immunohistochemistry: 1:50~1:100

Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk B (Phospho-Tyr706/Tyr707) antibody #11758 (left)or the same antibody preincubated with blocking peptide (right).
背景

Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Nakagawara A., Genomics 25:538-546(1995).
Shelton D.L., J. Neurosci. 15:477-491(1995).
Stoilov P., Biochem. Biophys. Res. Commun. 290:1054-1065(2002).

如果您使用该产品11758发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com