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位置: 首页 > 磷酸化抗体 > HP1γ (Phospho-Ser93) Antibody

HP1γ (Phospho-Ser93) Antibody#11768

HP1γ (Phospho-Ser93) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HP1γ (Phospho-Ser93) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of HP1γ only when phosphorylated at serine 93.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 93(R-L-S(p)-L-S) derived from Human HP1γ .

基因/蛋白名称HP1γ

修饰Phospho

别名HECH; HP1 gamma; HP1Hs-gamma; chromobox 3;

数据库入口号Swiss-Prot#: Q13185;
NCBI Gene#: 11335/653972;
NCBI Protein#: NP_009207.2.

UniprotQ13185

实际分子量24kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Western blotting: 1:500~1:1000

Western blot analysis of extracts from K562 cells treated with forskolin using HP1γ (Phospho-Ser93) Antibody #11768.The lane on the right is treated with the antigen-specific peptide.
背景

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Ye Q., J. Biol. Chem. 271:14653-14656(1996).
Ye Q., Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Koike N., FEBS Lett. 467:17-21(2000)

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

Email Address

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