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位置: 首页 > 磷酸化抗体 > MDC1 (Phospho-Ser513) Antibody

MDC1 (Phospho-Ser513) Antibody#11807

MDC1 (Phospho-Ser513) Antibody
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产品总价:
产品详情

产品名称MDC1 (Phospho-Ser513) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu

特异性The antibody detects endogenous levels of MDC1 only when phosphorylated at serine 513.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.

基因/蛋白名称MDC1

修饰Phospho

别名IER3; NFBD1; KIAA0170; DKFZp781A0122;

数据库入口号Swiss-Prot#: Q14676;
NCBI Gene#: 9656;
NCBI Protein#: NP_055456.2.

UniprotQ14676

实际分子量226kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Immunohistochemistry: 1:50~1:100

Immunohistochemical analysis of paraffin-embedded human brain tissue using MDC1 (Phospho-Ser513) antibody #11807 (left)or the same antibody preincubated with blocking peptide (right).
背景

The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

Nagase T., DNA Res. 3:17-24(1996).
Shiina T., Genetics 173:1555-1570(2006).
Mungall A.J., Nature 425:805-811(2003).

如果您使用该产品11807发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

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