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位置: 首页 > 磷酸化抗体 > Tip60 (Phospho-Ser90) Antibody

Tip60 (Phospho-Ser90) Antibody#11815

Tip60 (Phospho-Ser90) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Tip60 (Phospho-Ser90) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60.

基因/蛋白名称Tip60

修饰Phospho

别名 HTATIP; TI60; Tat-interactive protein-60;

数据库入口号Swiss-Prot#: Q92993;
NCBI Gene#: 10524;
NCBI Protein#: NP_006379.2.

UniprotQ92993

实际分子量58kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Immunohistochemistry: 1:50~1:100

Immunohistochemical analysis of paraffin-embedded human brain tissue using Tip60 (Phospho-Ser90) antibody #11815 (left)or the same antibody preincubated with blocking peptide (right).
背景

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Kamine J., Virology 216:357-366(1996).
Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).
Legube G., Gene 310:161-168(2003).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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