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SLC22A17 Antibody#37244

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SLC22A17 Antibody
SLC22A17 Antibody
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产品详情

产品名称SLC22A17 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用WB IHC

种属反应性Hu Mouse Rat

特异性The antibody detects endogenous levels of total SLC22A17 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to residues near the C terminal of human solute carrier family 22, member 17

基因/蛋白名称SLC22A17

别名BOCT; BOIT; 24p3R; NGALR; hBOIT; NGALR2; NGALR3

数据库入口号Swiss-Prot#: Q8WUG5
NCBI Gene ID: 51310
Gene Accssion: NP_065105.2

UniprotQ8WUG5

实际分子量56kd

浓度1.2mg/ml

配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

保存Store at -20˚C

应用详情

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Gel: 10%SDS-PAGE
Lysates (from left to right): Human esophagus cancer tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/600 dilution
Secondary antibody dilution: 1/8000
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #37244 at dilution 1/30.
背景

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

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应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com

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