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位置: 首页 > 磷酸化抗体 > Period Circadian Protein 2 (Phospho-Ser662) Antibody

Period Circadian Protein 2 (Phospho-Ser662) Antibody#12112

Period Circadian Protein 2 (Phospho-Ser662) Antibody
Period Circadian Protein 2 (Phospho-Ser662) Antibody
Period Circadian Protein 2 (Phospho-Ser662) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Period Circadian Protein 2 (Phospho-Ser662) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB IHC

种属反应性Hu Ms

特异性The antibody detects endogenous levels of Period Circadian Protein 2 only when phosphorylated at serine 662.

免疫原类型peptide

免疫原描述Peptide sequence around phosphorylation site of serine 662 (A-E-S(p)-V-A) derived from Human Period Circadian Protein 2.

基因/蛋白名称Period Circadian Protein 2

修饰Phospho

别名hPER2; KIAA0347; Period circadian protein 2

数据库入口号Swiss-Prot#:O15055;
NCBI Gene#:8864

UniprotO15055

实际分子量120kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from 3T3 cells, treated with PMA (125ng/ml, 30mins), using Period Circadian Protein 2 (Phospho-Ser662) antibody #12112. The lane on the right is treated with the synthesized peptide.
Western blot analysis of extracts from 3T3£¬HeLa and K562 cells, using Period Circadian Protein 2 (Phospho-Ser662) Antibody #12112. The lane on the left is treated with synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Period Circadian Protein 2 (Phospho-Ser662) antibody #12112. The picture on the right is treated with the synthesized peptide.
背景
Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers').

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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