免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 磷酸化抗体 > CREB (Phospho-Thr100) Antibody

CREB (Phospho-Thr100) Antibody#12133

CREB (Phospho-Thr100) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称CREB (Phospho-Thr100) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of CREB only when phosphorylated at threonine 100.

免疫原类型peptide

免疫原描述Peptide sequence around phosphorylation site of threonine 100 (S-G-T(p)-Q-I) derived from Human CREB.

基因/蛋白名称CREB

修饰Phospho

别名cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1

数据库入口号Swiss-Prot#:P16220;
NCBI Gene#:1385

UniprotP16220

实际分子量43kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using CREB (Phospho-Thr100) antibody #12133. The lane on the right is treated with the synthesized peptide.
背景
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

如果您使用该产品12133发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com