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位置: 首页 > 磷酸化抗体 > CSFR (Phospho-Tyr809) Antibody

CSFR (Phospho-Tyr809) Antibody#12135

CSFR (Phospho-Tyr809) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称CSFR (Phospho-Tyr809) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu

特异性The antibody detects endogenous levels of CSFR only when phosphorylated at tyrosine 809.

免疫原描述Peptide sequence around phosphorylation site of tyrosine 809 (S-N-Y(p)-I-V) derived from Human CSFR.

基因/蛋白名称CSFR

修饰Phospho

别名CD115; CSF-1-R; CSF1R; CSFMR; EC 2.7.10.1; FMS; Fms proto-oncogene; M-CSFR; Macrophage colony stimulating factor I receptor precursor; c-fms; kinase CSFR

数据库入口号Swiss-Prot#:P07333;
NCBI Gene#:1436

UniprotP07333

计算分子量107kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情

Immunohistochemistry: 1:50~1:100

Immunohistochemistry analysis of paraffin-embedded human brain tissue using CSFR (Phospho-Tyr809) antibody #12135. The picture on the right is treated with the synthesized peptide.
背景

Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. 

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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