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位置: 首页 > 磷酸化抗体 > Vitamin D3 Receptor (Phospho-Ser51) Antibody

Vitamin D3 Receptor (Phospho-Ser51) Antibody#12155

Vitamin D3 Receptor (Phospho-Ser51) Antibody
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产品总价:
产品详情

产品名称Vitamin D3 Receptor (Phospho-Ser51) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of Vitamin D3 Receptor only when phosphorylated at serine 51.

免疫原类型peptide

免疫原描述Peptide sequence around phosphorylation site of serine 51 (R-R-S(p)-M-K) derived from Human Vitamin D3 Receptor.

基因/蛋白名称Vitamin D3 Receptor

修饰Phospho

别名1;25-dihydroxyvitamin D3 receptor; NR1I1; vitamin D receptor; vitamin D3 receptor

数据库入口号Swiss-Prot#:P11473;
NCBI Gene#:7421

UniprotP11473

实际分子量38kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from COLO cells, treated with Insulin (0.01U/ml, 15mins), using Vitamin D3 Receptor (Phospho-Ser51) antibody #12155. The lane on the right is treated with the synthesized peptide.
背景
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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