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位置: 首页 > 磷酸化抗体 > WAVE1 (Phospho-Tyr125) Antibody

WAVE1 (Phospho-Tyr125) Antibody #12156

WAVE1 (Phospho-Tyr125) Antibody
WAVE1 (Phospho-Tyr125) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称WAVE1 (Phospho-Tyr125) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB IHC

种属反应性Hu Ms

特异性The antibody detects endogenous levels of WAVE1 only when phosphorylated at tyrosine 125.

免疫原类型peptide

免疫原描述Peptide sequence around phosphorylation site of tyrosine 125 (E-T-Y(p)-D-V) derived from Human WAVE1.

基因/蛋白名称WAVE1

修饰Phospho

别名KIAA0269; SCAR1; Verprolin homology domain-containing protein 1; WAS1; WASF1; WASP-family protein member 1; Wiskott-Aldrich syndrome protein family member 1

数据库入口号Swiss-Prot#:Q92558;
NCBI Gene#:8936

UniprotQ92558

实际分子量70kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from NIH/3T3 cells, treated with Insulin (0.01U/ml, 15mins), using WAVE1 (Phospho-Tyr125) antibody #12156. The lane on the right is treated with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using WAVE1 (Phospho-Tyr125) antibody #12156. The picture on the right is treated with the synthesized peptide.
背景
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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