免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 磷酸化抗体 > RB(Phospho-Ser811) antibody

RB(Phospho-Ser811) antibody#12173

RB(Phospho-Ser811) antibody
是否有货: ����2��
产品总价:
产品详情

产品名称RB(Phospho-Ser811) antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB

种属反应性Human

特异性The antibody detects endogenous level of RB only when phosphorylated at serine 811.

免疫原类型Peptide

免疫原描述A synthetic phosphorylated peptide around S811 of human RB (NP_000312.2).

基因/蛋白名称RB

修饰Phospho

别名OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb

数据库入口号Uniprot:P06400
GeneID:5925

UniprotP06400

Gene ID5925

实际分子量106kDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:1000 - 1:2000
Western blot analysis of extracts of HeLa cells, using Phospho-RB-S811 antibody.
背景
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

如果您使用该产品12173发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com