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DNMT3L antibody#38399

DNMT3L antibody
DNMT3L antibody
DNMT3L antibody
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产品总价:
产品详情

产品名称DNMT3L antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total DNMT3L protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fusion protein of human DNMT3L (NP_787063.1).

基因/蛋白名称DNMT3L

别名DNMT3L

数据库入口号Uniprot:Q9UJW3
GeneID:29947

UniprotQ9UJW3

Gene ID29947

实际分子量/

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded rat testis using DNMT3L antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using DNMT3L antibody.
Immunohistochemistry of paraffin-embedded mouse brain using DNMT3L antibody.
背景
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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