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LEPR antibody#38530

LEPR antibody
LEPR antibody
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产品总价:
产品详情

产品名称LEPR antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF

种属反应性Human,Rat

特异性The antibody detects endogenous level of total LEPR protein.

免疫原类型Peptide

免疫原描述A synthetic peptide of human LEPR

基因/蛋白名称LEPR

别名CD295;LEP-R;LEPRD;OB-R;OBR;LEPR

数据库入口号Uniprot:P48357
GeneID:3953

UniprotP48357

Gene ID3953

实际分子量140KDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:1000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Leptin Receptor antibody.
Immunofluorescence analysis of HepG2 cells using Leptin Receptor Rabbit pAb.
背景
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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