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ELF3 antibody#38856

ELF3 antibody
ELF3 antibody
ELF3 antibody
ELF3 antibody
是否有货: ����2��
产品总价:
产品详情

产品名称ELF3 antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total ELF3 protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fusion protein of human ESE1/ESE1/ELF3 (NP_004424.3).

基因/蛋白名称ELF3

别名ELF3;EPR-1;ERT;ESE-1;ESX

数据库入口号Uniprot:P78545
GeneID:1999

UniprotP78545

Gene ID1999

实际分子量42kDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using ESE1/ESE1/ELF3 antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using ESE1/ELF3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse kidney using ESE1/ELF3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat lung using ESE1/ELF3 Rabbit pAb.
背景
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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