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CD177 antibody#39002

CD177 antibody
CD177 antibody
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产品总价:
产品详情

产品名称CD177 antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB,IHC,IF

种属反应性Human,Mouse

特异性The antibody detects endogenous level of total CD177 protein.

免疫原类型Recombinant Protein

免疫原描述The antiserum was produced against synthesized peptide derived from the Internal region of human CD177.

基因/蛋白名称CD177

别名NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP;

数据库入口号Swiss-Prot#: Q8N6Q3
NCBI Gene ID: 57126

UniprotQ8N6Q3

实际分子量46kd

浓度1.0mg/ml

配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

保存Store at -20˚C

应用详情

WB 1:500 - 1:2000 IHC: 1:100-300  IF 1:50-200

Western blot analysis of lysate from K562 cells, using CD177 Antibody.
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
背景

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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