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位置: 首页 > 磷酸化抗体 > LATS2 (Phospho-Ser872) Antibody

LATS2 (Phospho-Ser872) Antibody#12875

LATS2 (Phospho-Ser872) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称LATS2 (Phospho-Ser872) Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB

种属反应性Hu Ms Rt

特异性Phospho-LATS2 (S872) Antibody detects endogenous levels of LATS2 only when phosphorylated at S872

免疫原类型Peptide-KLH

免疫原描述A synthesized peptide derived from human LATS2 (Phospho-Ser872)

别名FLJ13161 antibody Kinase phosphorylated during mitosis protein antibody KPM antibody Large tumor suppressor homolog 2 antibody Large tumor suppressor homolog 2 Drosophila antibody Large tumor suppressor kinase 2 antibody LATS large tumor suppressor Drosophila homolog 2 antibody LATS large tumor suppressor homolog 2 antibody Lats2 antibody LATS2_HUMAN antibody Serine threonine kinase kpm antibody Serine threonine protein kinase kpm antibody Serine threonine-protein kinase kpm antibody Serine threonine-protein kinase LATS2 antibody Warts like kinase antibody Warts-like kinase antibody

数据库入口号Swiss-Prot#:Q9NRM7
NCBI Gene ID26524

计算分子量150

浓度1.0mg mL

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
WB dilution:1:1000
Western blot analysis LATS2 (Phospho-Ser872) using EGF treated 293 whole cell lysates
产品描述
LATS2 is an AGC kinase of the NDR family of kinases. It is a tumor suppressor of the LATS family, and plays a critical role in centrosome duplication, maintenance of mitotic fidelity, and genomic stability (1). LATS2 inhibits cell growth at the G1,S transition by down-regulating cyclin E,CDK2 kinase activity (2). It also plays an important role in regulation of the Hippo pathway, a pathway that is important in controlling organ size and tumor progression by regulating cellular proliferation and promoting apoptosis (3,4,5)?

如果您使用该产品12875发表了文章,请通知我们,让我们可以引用您的文献。

et al,Identification of the kInase STK25 as an upstream activator of LATS signalIng. In Nat Commun on 2019 Apr 4 by Lim S, Hermance N, et al..PMID:30948712, , (2019),
PMID: 30948712
et al,The CalcR-PKA-Yap1 Axis Is Critical for MaIntaInIng Quiescence In Muscle Stem Cells. In Cell Rep on 2019 Nov 19 by Zhang L, Noguchi YT, et al..PMID:31747590, , (2019),
PMID: 31747590
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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