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位置: 首页 > 磷酸化抗体 > p90RSK(Phospho-Ser352) Antibody

p90RSK(Phospho-Ser352) Antibody#11113

p90RSK(Phospho-Ser352) Antibody
p90RSK(Phospho-Ser352) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称p90RSK(Phospho-Ser352) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of p90RSK only when phosphorylated at serine 352.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine 352 (R-D-S(p)-P-G) derived from Human p90RSK.

基因/蛋白名称p90RSK

修饰Phospho

别名KS6A1; MAPKAP-K1a; RPS6KA1; RSK-1; RSK1

数据库入口号Swiss-Prot: Q15418
NCBI Protein: NP_001006666.1

UniprotQ15418

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 90kd
Western blotting: 1:500~1:1000

Western blot analysis of extracts from HUVEC cells using p90RSK(Phospho-Ser352) Antibody #11113(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
Western blot analysis of extracts from Hela cells, treated with PMA or calf intestinal phosphatase (CIP), using p90RSK (Phospho-Ser352) Antibody #11113.
背景

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

Silverman E, et al. Mol Cell Biol. 2004 Dec; 24(24): 10573-10583.
Itoh S, et al. J Biol Chem 2005 Jun 24; 280(25): 24135-24142
Eisenmann KM, et al. Cancer Res 2003 Dec 01; 63(23): 8330-7

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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