产品详情
产品名称LT-alpha Antibody
来源种属Mouse
克隆性Monoclonal
克隆号6-C10-10
纯化ProA affinity purified
应用WB
种属反应性Hu, Rt
免疫原描述peptide
别名LTalpha antibody DIF antibody LT alpha antibody LT antibody LT-alpha antibody Lta antibody Lymphotoxin alpha (TNF superfamily, member 1) antibody Lymphotoxin alpha antibody Lymphotoxin-alpha antibody TNF B antibody TNF superfamily member 1 antibody TNF, lymphocyte-derived antibody TNF-beta antibody TNFB antibody TNFB_HUMAN antibody TNFbeta antibody TNFSF1 antibody TNLG1E antibody Tumor necrosis factor beta antibody tumor necrosis factor ligand 1E antibody Tumor necrosis factor ligand superfamily member 1 antibody
数据库入口号Swiss-Prot#:P01374
计算分子量18 kDa
配方1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
背景
Lymphotoxin-alpha (LTA), a member of the tumor necrosis factor (TNF) family of cytokines, was initially isolated on the basis of an anti-tumor activity. LTA plays a key role in communication between lymphocytes and stromal cells, thereby eliciting cytotoxic effects on cancer cells. It induces the expression of vascular cell-adhesion molecule 1 (VCAM1) on vascular endothelial cells and recruits natural killer (NK) cells to parenchymal organs and tumor lesions.
背景文献
1. Bell G.I., Pictet R.L., Rutter W.J., Cordell B., Tischer E., Goodman H.M.;"Sequence of the human insulin gene.";Nature 284:26-32(1980). 2. Nicol D.S.H.W., Smith L.F.;"Amino-acid sequence of human insulin.";Nature 187:483-485(1960). 3. Chang X., Joergensen A.M., Bardrum P., Led J.J.;"Solution structures of the R6 human insulin hexamer."; Biochemistry 36:9409-9422(1997).
Yes
