产品详情
产品名称DUSP5 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Immunogen affinity purified
应用WB, ICC
种属反应性Hu,Ms
免疫原描述peptide
别名Dual specificity phosphatase 5 antibody Dual specificity protein phosphatase 5 antibody Dual specificity protein phosphatase hVH 3 antibody Dual specificity protein phosphatase hVH3 antibody DUS5_HUMAN antibody DUSP 5 antibody DUSP antibody DUSP5 antibody HVH 3 antibody HVH3 antibody Serine/threonine specific protein phosphatase antibody VH 3 antibody VH1 like phosphatase 3 antibody VH3 antibody
数据库入口号Swiss-Prot#:Q16690
计算分子量42kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:500
ICC: 1:50
背景
Dual specificity protein phosphatase 5 is encoded by the DUSP5 gene, which is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
背景文献
1."Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines."Kwak S.P., Dixon J.E.J. Biol. Chem. 270:1156-1160(1995) 2."A novel dual specificity phosphatase induced by serum stimulation and heat shock."Ishibashi T., Bottaro D.P., Michieli P., Kelley C.A., Aaronson S.A.J. Biol. Chem. 269:29897-29902(1994)
Yes
