产品详情
产品名称VEGF Recepr 2 Antibody
来源种属Mouse
克隆性Monoclonal
克隆号2G5
纯化ProA affinity purified
应用WB, IP, IF, IHC(P)
种属反应性Hu, Ms, Rt
免疫原描述peptide
别名CD309 antibody CD309 antigen antibody EC 2.7.10.1 antibody Fetal liver kinase 1 antibody FLK-1 antibody FLK1 antibody FLK1, mouse, homolog of antibody Kdr antibody Kinase insert domain receptor (a type III receptor tyrosine kinase) antibody Kinase insert domain receptor antibody KRD1 antibody Ly73 antibody Protein tyrosine kinase receptor FLK1 antibody Protein-tyrosine kinase receptor flk-1 antibody soluble VEGFR2 antibody Tyrosine kinase growth factor receptor antibody Vascular endothelial growth factor receptor 2 antibody VEGFR 2 antibody VEGFR antibody VEGFR-2 antibody VEGFR2 antibody VGFR2_HUMAN antibody
数据库入口号Swiss-Prot#:P35918
计算分子量150 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000
IHC: 1:50-500
IP: 1-2 μg per 100-500 μg of total protein
背景
Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1),Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1,it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
背景文献
1. Murohara, T., et al. 2000. Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J. Clin. Invest. 105:1527-1536. 2. Li, X., et al. 2011. Calcineurin-NFAT signaling critically regulates early lineage specification in mouse embryonic stem cells and embryos. Cell Stem Cell 8: 46-58.
Yes
