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Dysferlin (DYSF) Antibody#48508

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Dysferlin (DYSF) Antibody
Dysferlin (DYSF) Antibody
Dysferlin (DYSF) Antibody
Dysferlin (DYSF) Antibody
Dysferlin (DYSF) Antibody
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产品详情

产品名称Dysferlin (DYSF) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Protein affinity purified

应用WB,IHC,FC

种属反应性Hu

免疫原描述Recombinant protein

别名DMAT antibody
DYSF antibody
DYSF_HUMAN antibody
Dysferlin antibody
Dysferlin limb girdle muscular dystrophy 2B (autosomal recessive) antibody
Dysferlin limb girdle muscular dystrophy 2B antibody
Dystrophy associated fer 1 like 1 antibody
Dystrophy associated fer 1 like protein antibody
Dystrophy associated fer1 like 1 antibody
Dystrophy associated fer1 like protein antibody
Dystrophy-associated fer-1-like protein antibody
Fer 1 like protein 1 antibody
Fer-1-like protein 1 antibody
Fer1 like protein 1 antibody
FER1L1 antibody
FLJ00175 antibody
FLJ90168 antibody
LGMD 2B antibody
LGMD2B antibody
Limb girdle muscular dystrophy 2B (autosomal recessive) antibody
Limb girdle muscular dystrophy 2B antibody
Miyoshi myopathy antibody
MM antibody
MMD1 antibody

数据库入口号Swiss-Prot#:O75923

计算分子量237 kDa

配方1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情
WB: 1:500-1:2,000
IHC: 1:50-1:200


FC: 1:50-1:100
Western blot analysis of Dysferlin on human fetal skeletal muscle tissue lysate using anti-Dysferlin antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Dysferlin antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-Dysferlin antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-Dysferlin antibody. Counter stained with hematoxylin.
Flow cytometric analysis of HUVEC cells with Dysferlin antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
背景
Key calcium ion sensor involved in the Ca2+-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.
背景文献
1. Fuson K et al. Alternate splicing of dysferlin C2A confers Ca(2+)-dependent and Ca(2+)-independent binding for membrane repair. Structure 22:104-115 (2014).
2. Huang Y et al. AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration. FASEB J 21:732-742 (2007).

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5

操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡

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