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位置： 首页 > 重组兔单抗 > PSD95 Rabbit mAb

PSD95 Rabbit mAb#48638

评价
Recombinant
查看说明书
PSD95 Rabbit mAb
PSD95 Rabbit mAb
PSD95 Rabbit mAb
PSD95 Rabbit mAb
PSD95 Rabbit mAb
PSD95 Rabbit mAb
是否有货： Yes
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产品详情

产品名称PSD95 Rabbit mAb

克隆号SR38-09

纯化Affinity-chromatography

应用WB, ICC/IF, IHC, IP, FC

种属反应性Hu, Ms, Rt

免疫原描述A synthesized peptide derived from human Disks large homolog 4

别名Discs large homolog 4 antibody
Disks large homolog 4 antibody
DLG 4 antibody
Dlg4 antibody
DLG4_HUMAN antibody
FLJ97752 antibody
FLJ98574 antibody
Human post synaptic density protein 95 antibody
Post synaptic density protein 95 antibody
Postsynaptic density protein 95 antibody
PSD 95 antibody
PSD-95 antibody
PSD95 antibody
SAP 90 antibody
SAP-90 antibody
SAP90 antibody
Synapse associated protein 90 antibody
Synapse-associated protein 90 antibody
Tax interaction protein 15 antibody

数据库入口号Swiss-Prot#:P78352

计算分子量100 kDa

配方Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

保存Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

应用详情
WB 1:1000-1:2000
IHC 1:100-1:200
ICC/IF 1:50-1:200
IP 1:20-1:50
FC 1:20-1:100
Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-PSD95 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded rat cerebellum tissue using anti-PSD95 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse cerebullum tissue using anti-PSD95 antibody. Counter stained with hematoxylin.

Flow cytometric analysis of SH-SY-5Y cells with PSD95 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Western blot analysis of PSD95 expression in Mouse brain tissue lysate.
Immunofluorescent analysis of U87-MG cells, using PSD95 Antibody .
背景

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons.

背景文献

1. Planagum�� J et al. Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice. Brain 138:94-109 (2015).
2. Zhou L et al. Neonatal exposure to sevoflurane may not cause learning and memory deficits and behavioral abnormality in the childhood of Cynomolgus monkeys. Sci Rep 5:11145 (2015).

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5

操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡

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