The RING-type zinc finger protein Rad18 is essential in post-replication repair of damaged DNA and contributes to the maintenance of genomic stability. Rad18 maintains chromosomal DNA with the Rad54-dependent DNA repair pathway and recruits ubiquitin-conjugating enzymes in the Rad6 pathway. Rad18 functions in gap-filling of a daughter strand on replication of damaged DNA and is localized in the nucleus.
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2. Shoaib M et al. PUB-NChIP--in vivo biotinylation" approach to study chromatin in proximity to a protein of interest. Genome Res 23:331-40 (2013).,,,, 151953,151953,49045,,MMP11 Rabbit mAb,Rabbit,Monoclonal,SN74-08,,ProA affinity purified,"WB, ICC/IF, IHC