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位置： 首页 > 重组兔单抗 > VE Cadherin Rabbit mAb

VE Cadherin Rabbit mAb#49308

评价
Recombinant
查看说明书
VE Cadherin Rabbit mAb
是否有货： Yes
产品总价:
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产品详情

产品名称VE Cadherin Rabbit mAb

来源种属Recombinant Rabbit

克隆性 Monoclonal antibody

克隆号JJ0941

纯化ProA affinity purified

应用WB,IP

种属反应性Ms

免疫原描述recombinant protein

别名7B 4 antibody
7B4 antibody
7B4 antigen antibody
CADH5_HUMAN antibody
Cadherin 5 antibody
Cadherin 5 type 2 antibody
Cadherin 5, type 2 (vascular endothelium) antibody
Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody
cadherin, vascular endothelial antibody
cadherin, vascular endothelial, 1 antibody
Cadherin-5 antibody
Cadherin5 antibody
CD 144 antibody
CD144 antibody
CD144 antigen antibody
CDH 5 antibody
CDH5 antibody
CDH5 protein antibody
Endothelial specific cadherin antibody
FLJ17376 antibody
OTTHUMP00000174777 antibody
Vascular endothelial cadherin antibody
Vascular epithelium cadherin antibody
VE Cad antibody
VE-cadherin antibody
VEC antibody

数据库入口号Swiss-Prot#:P55284

计算分子量88/125 kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情
WB: 1:1,000-5,000



Western blot analysis of VE Cadherin on different lysates using anti-VE Cadherin antibody at 1/1,000 dilution. Positive control:
Lane 1: Mouse heart
Lane 2: Mouse placenta
Lane 3: Mouse spleen
Lane 4: Mouse lung
背景
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
背景文献
1. Ye X et al. Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma. J Pathol 239:139-51 (2016).
2. Li C et al. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix. Nat Commun 7:11455 (2016).

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5

操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡

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