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位置: 首页 > 重组兔单抗 > EAAT3 Rabbit mAb

EAAT3 Rabbit mAb#49741

评价
Recombinant
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
EAAT3 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称EAAT3 Rabbit mAb

来源种属Recombinant Rabbit

克隆性 Monoclonal antibody

克隆号JU39-69

纯化ProA affinity purified

应用WB,ICC,IF,IHC

种属反应性Hu, Ms, Rt

免疫原描述Recombinant protein

别名EAA3_HUMAN antibody
EAAC 1 antibody
EAAC1 antibody
EAAT 3 antibody
Excitatory amino acid carrier 1 antibody
Excitatory amino acid carrier1 antibody
Excitatory amino acid transporter 3 antibody
Excitatory amino acid transporter3 antibody
Excitatory amino-acid carrier 1 antibody
GLUTAMATE TRANSPORTER, HIGH-AFFINITY antibody
MEAAC 1 antibody
MEAAC1 antibody
Neuronal and epithelial glutamate transporter antibody
REAAC 1 antibody
REAAC1 antibody
Slc1 a1 antibody
Slc1a 1 antibody
SLC1A1 antibody
Sodium dependent glutamate/aspartate transporter 3 antibody
Sodium-dependent glutamate/aspartate transporter 3 antibody
Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1 antibody
SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 antibody
Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody
Solute carrier family 1 member 1 antibody
Solute carrier family 1, member 1 antibody

数据库入口号Swiss-Prot#:P43005

计算分子量57 kDa (Predicted band size)

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情
WB: 1:500
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Western blot analysis of EAAT3 on mouse liver tissue lysate using anti-EAAT3 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-EAAT3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-EAAT3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-EAAT3 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-EAAT3 antibody. Counter stained with hematoxylin.
ICC staining EAAT3 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining EAAT3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining EAAT3 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
背景
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Negatively regulated by ARL6IP5.
背景文献
1. Kanai Y et al. The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport. J Biol Chem 269:20599-20606 (1994).
2. Arriza J L et al. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14:5559-5569 (1994).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

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