产品详情
产品名称Timp1 Monoclonal Antibody
来源种属Mouse
克隆性Monoclonal
纯化protein G purifed
应用WB
种属反应性Hu
特异性specific for Human Timp1 denatured and native forms
免疫原类型protein
免疫原描述human Timp 1
基因/蛋白名称Timp1
别名timp-1
数据库入口号Swiss-Prot#: P01033
UniprotP01033
计算分子量23kd
浓度1.0mg/mL
配方Preservative: 15mmol/L NaN3Constituents: 0.1mol/L Nacl, 50% glycerol
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
All lanes :Mouse anti-Human Timp1 monoclonal antibody at 1ug/ml
Lane 1: HepG-2 cell lysate
Predicted band size : 23 kDa
Observed band size : 23 kDa
Additional bands at£º50KD£¨We are unsure as to the identity of this extra band.£©
All lanes : Mouse anti-Human Timp1 monoclonal antibody at 1ug/ml
Lane 1: TIMP1 transfected pichia Yeast cell lysate
Predicted band size : 23 kDa
Observed band size : 23 kDa
Immunohistochemical analysis of paraffin-embedded human prostate cancer using #42030 at dilution of 1:100.
背景
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
背景文献
[1] Docherty A.J.P., Lyons A., Smith B.J., Wright E.M., Stephens P.E., Harris T.J.R.,Murphy G., Reynolds J.J.Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318:66-69(1985) [2] Gasson
yes
