产品详情
产品名称Leukocyte elastase inhibitor Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Caprylic Acid Ammonium Sulfate Precipitation purified
应用IHC
种属反应性Hu
特异性The antibody detects endogenous level of total Leukocyte elastase inhibitor polyclonal antibody.
免疫原类型protein
免疫原描述Recombinant human Leukocyte elastase inhibitor protein£¨1-379aa£©
基因/蛋白名称Leukocyte elastase inhibitor
别名Monocyte/neutrophil elastase inhibitor, Peptidase inhibitor 2, ELANH2, MNEI, PI2, SERPINB1
数据库入口号Swiss-Prot#: P30740
UniprotP30740
配方Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:20 - 1:200
背景
Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H.
背景文献
[1]"Identification of SERPINB1 as a physiological inhibitor of human granzyme H." Wang L., Li Q., Wu L., Liu S., Zhang Y., Yang X., Zhu P., Zhang H., Zhang K., Lou J., Liu P., Tong L., Sun F., Fan Z. J. Immunol. 190:1319-1330(2013). [2]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB." Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R. Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012). [3]"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011).
货期1周
