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位置: 首页 > 抗体 > Vascular cell adhesion protein 1 Polyclonal Antibody

Vascular cell adhesion protein 1 Polyclonal Antibody#42485

Vascular cell adhesion protein 1 Polyclonal Antibody
是否有货: 货期1周
产品总价:
产品详情

产品名称Vascular cell adhesion protein 1 Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Caprylic Acid Ammonium Sulfate Precipitation purified

应用IHC

种属反应性Hu

特异性The antibody detects endogenous level of total Vascular cell adhesion protein 1 polyclonal antibody.

免疫原类型protein

免疫原描述Recombinant human Vascular cell adhesion protein 1 protein

基因/蛋白名称Vascular cell adhesion protein 1

别名INCAM-100, CD_antigen=CD106 VCAM1, L1CAM

数据库入口号Swiss-Prot#: P19320

UniprotP19320

配方Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

保存Store at -20˚C

应用详情

Immunohistochemistry: 1:20 - 1:200
Immunohistochemical analysis of paraffin-embedded human colon cancer using #42485 at dilution of 1:20.
背景
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
背景文献
[1]Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.Osborn L., Hession C., Tizard R., Vassallo C., Luhowskyj S., Chi-Rosso G., Lobb R.Cell 59:1203-1211(1989) [2]Full length

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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