产品详情
产品名称Collagen Type IV Antibody
来源种属Mouse
克隆性Monoclonal
克隆号IHC549
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Collagen Type IV is a primary component in the basal lamina that is used as a marker to observe the presence of the lamina and examine its structure. In addition to the epithelial basal lamina, Anti-Collagen Type IV stains mesenchymal components. It is useful for identifying soft tissue cancers including schwannomas and leiomyomas. Anti-Collagen Type IV frequently reacts with these tissues after becoming well-differentiated and malignant. The use of Anti-Collagen Type IV produces more reliable results than non-specific silver reticulum stains when investigating the vascular elements of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma.
背景文献
Gould VE, et al. Pathol Annul. 1976; 11:353-86.
McArdle JP, et al. Int J Cancer. 1984: 34:633-8.
Sakr WA, et al. Hum Pathol. 1987; 18:1043-50.
Barsky SH, et al. Am J Surg Pathol. 1983; 7:667-77.
De Iorio P, et al. Anticancer Res. 2001; 21:1395-9.
Maatta M, et al. J Histochem Cytochem. 2001; 49:711-26.
Schmehl K, et al. Int J Colorectal Dis. 2000; 15:39-48.
Felix A, et al. Hum Pathol. 1999; 30:964-9.
Damiani S, et al. Virchows Arch. 1999; 434:227-34.