产品详情
产品名称Annexin A1 Antibody
来源种属Mouse
克隆性Monoclonal
克隆号IHC512
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Annexin A1 (ANXA1) is a membrane protein that plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandins, and leukotriene mediators. This target is overexpressed in 97% of all samples from patients with with hairy cell leukemia, and is absent in other B-cell lymphomas. High ANXA1 expression is frequently associated with advanced stage esophageal and esophagogastric junction adenocarcinoma, and is also linked to advanced and metastatic disease states.
背景文献
Tiacci E, et al. N Eng J Med. 2011; 364:2305-2315.
Wang K, et al. Clin Cancer Res. 2006; 12:4598-4604.
in stock (1 week)
