产品详情
产品名称CD22 Antibody
来源种属Mouse
克隆性Monoclonal
克隆号IHC022
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Cluster of differentiation 22 (CD22) is a glycoprotein that appears on the cell membrane of B-cells and the cytoplasm of late pro- and early pre-B lymphocytes. Anti-CD22 is a useful pan-B reagent that allows for the identification of neoplastic and normal B lymphocytes in the peripheral blood. CD22 is overexpressed in hairy cell leukemia. Expression is only present in the late stages of B-lymphocyte differentiation, and therefore may support the identification of mature B-cell leukemia. Some studies have suggested that CD22 may be involved in metastasis of lung cancer cells.
背景文献
Abdel-Ghafar A, et al. Hematol Rep. 2012; 4:e3
Tuscano J, et al. Cancer Res. 2012; 72:5556-65.
Shao H, et al. Leuk Res. 2013; 37:401-409.
4 weeks
