产品详情
产品名称MUC5AC Antibody
来源种属Mouse
克隆性Monoclonal
克隆号IHC625
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Mucin 5AC (MUC5AC) is a secretory-type mucin found in columnar mucous cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon, but not in normal colon cells. MUC5AC expression is indicated in carcinomas wherein the type is defined as diffuse and infiltrative, and those located mainly in the antrum. Studies have also suggested a correlation between MUC5AC and colorectal signet-ring cell carcinoma, with overexpression of MUC5AC relating to the carcinogenesis, malignant potential, progression, and clinical behaviors.
背景文献
Fetsch PA, et al. Cancer. 1998; 84:101-8.
Ichihara T, et al. Cancer. 1988; 61:324-33.
Soslow RA, et al. Int J Gynecol Pathol. 1996; 15:257-65.
Charpin C, et al. Int J Gynecol Pathol. 1982; 1:231-45.
Reis CA, et al. Int J Cancer. 1997; 74:112-21.
Kim GE, et al. Gastroenterology. 2002; 123:1052-60.
Chaves P, et al. Dis Esophagus. 2005; 18:383-7.
Leteurtre E, et al. World J Gastroenterol. 2006; 12:3324-31.
Mino-Kenudson M, et al. Arch Pathol Lab Med. 2007; 131:86-90.
Mizoshita T, et al. Histol Histopathol. 2007; 22:251-60.
OConnell FP, et al. Arch Pathol Lab Med. 2005; 129:338-47.
Park SY, et al. Arch Pathol Lab Med. 2007; 131:1561-7.
Rakha EA, et al. Mod Pathol. 2005; 18:1295-304.