产品详情
产品名称TFE3 Antibody
来源种属Mouse
克隆性Monoclonal
克隆号IHC672
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Transcription Factor E3 (TFE3) is a transcription factor that binds to the MUE3-type E-box sequences involved in TGF- signalling. Anti-TFE3 staining is the most sensitive and specific indicator of Xp11 translocation renal cell carcinomas. Since alveolar soft part sarcoma (ASPS) is characterized by a specific chromosomal rearrangement resulting in a chimeric transcription factor (ASPSCR1-TFE3), this TFE3 IVD antibody is also a useful diagnostic tool for recognizing ASPS.
背景文献
Argani P, et al. Am J Clin Pathol. 2006; 126:332-4.
Argani P, et al. Am J Surg Pathol. 2003; 27:750-61.
Lazar AJ, et al. Histopathology. 2009; 55:750-5.
in stock (1 week)
