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位置: 首页 > 标记抗体 > PI3-kinase p85- alpha (Phospho-Tyr607) Conjugated Antibody

PI3-kinase p85- alpha (Phospho-Tyr607) Conjugated Antibody#C12057

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称PI3-kinase p85- alpha (Phospho-Tyr607) Conjugated Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB,IHC,IF,ELISA

种属反应性Human,Mouse,Rat,Chicken

特异性The antibody detects endogenous level of PI3-kinase p85- alpha only when phosphorylated at Tyrosine 607.

免疫原描述Peptide sequence around phosphorylation site of Tyrosine 607 (D-Q-Y(p)-S-L) derived from Human PI3-kinase p85-alpha.

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名p85;AGM7;GRB1;p85-ALPHA

数据库入口号Swiss-Prot#:P27986
NCBI Gene ID:5295
NCBI mRNA#:NM_001242466.1
NCBI Protein#:NP_001229395.1?

计算分子量80

浓度

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚Cin dark for 6 months

应用详情

WB: 1:50-1:200
IF:1:50-1:200

产品描述

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

背景

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com