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位置: 首页 > 标记抗体 > JNK Conjugated Antibody

JNK Conjugated Antibody#C48335

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称JNK Conjugated Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB, IF, FC

种属反应性Hu, Ms, Rt

免疫原描述Amino acids 1-384 representing full length JNK1 of human origin.

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名AI849689 antibody
c Jun N terminal kinase 1 antibody
C-JUN kinase 1 antibody
c-Jun N-terminal kinase 1 antibody
EC 2.7.11.24 antibody
JNK 1 antibody
JNK antibody
JNK-46 antibody
JNK1A2 antibody
JNK21B1/2 antibody
MAP kinase 8 antibody
MAPK 8 antibody
mapk8 antibody
Mitogen activated protein kinase 8 antibody
Mitogen-activated protein kinase 8 antibody
MK08_HUMAN antibody
p54 gamma antibody
Prkm8 antibody
Protein kinase JNK1 antibody
Protein kinase, mitogen-activated, 8 antibody
SAPK 1 antibody
SAPK gamma antibody
SAPK1 antibody
Stress-activated protein kinase 1 antibody
Stress-activated protein kinase JNK1 antibody

数据库入口号Swiss-Prot#:P45983

计算分子量46/54kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情
WB: 1:50-1:200
IF:1:50-1:200
FC: 1:50-1:200
背景
c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1, JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com