YAP65 Conjugated Antibody - SAB | Signalway Antibody

产品详情图片产品描述发表文献(0) 其它

产品详情

产品名称YAP65 Conjugated Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB, IF

种属反应性Hu, Ms, Rt

免疫原描述Amino acids 206-330 mapping near the C-terminus of YAP of human origin.

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名65 kDa Yes associated protein antibody
65 kDa Yes-associated protein antibody
COB1 antibody
YAp 1 antibody
YAP 65 antibody
YAP antibody
YAP1 antibody
YAP1_HUMAN antibody
YAP2 antibody
YAP65 antibody
yes -associated protein delta antibody
Yes associated protein 1 65kDa antibody
Yes associated protein 1 antibody
Yes associated protein 2 antibody
yes associated protein beta antibody
YKI antibody
Yorkie homolog antibody

数据库入口号Swiss-Prot#:P46937

计算分子量65kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情

WB: 1:50-1:200
IF:1:50-1:200

背景

The Yes-associated protein, otherwise known as YAP, is a 14-3-3-binding molecule that was originally recognized by virtue of its ability to bind to the SH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylation of a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. YAP may link events at the plasma membrane and cytoskeleton to inhibition of transcription in the nucleus in a manner regulated by 14-3-3 proteins. YAP shares homology with the WW domain of TAZ, transcriptional co-activator with PDZ-binding motif, which functions as a transcriptional co-activator by binding to the PPXY motif present in transcription factors. YAP is expressed at high levels in the lung, placenta, prostate, ovary and testis.

如果您使用该产品C48351发表了文章，请通知我们，让我们可以引用您的文献。

操作手册

注释

应用

WB免疫印迹
IHC免疫组化
IF免疫荧光
ICC免疫细胞化学
FC流式细胞
IP免疫沉淀
E酶联免疫吸附法
DB免疫斑点法
ChIP染色质免疫沉淀
GICA胶体金免疫层析法
NC阴性对照

种属反应性

Hu人
Ms小鼠
Rt大鼠
Dm果蝇
C线虫
Mk猴
Rb兔
B牛
D狗
P猪
Hm仓鼠
ChHm中国仓鼠
Chk鸡

首页

抗体

ELISA试剂盒

生化试剂盒

重组蛋白

定制服务

新闻动态

关于我们

YAP65 Conjugated Antibody#C48351

操作手册

注释

应用

种属反应性

联系我们

Location :

Phone :

Email Address

帮助与技术支持

快速导航

YAP65 Conjugated Antibody#C48351

操作手册

注释

应用

种属反应性

联系我们

Location :

Phone :

Email Address

帮助与技术支持

快速导航

邮件订阅