VEGF Conjugated Antibody - SAB | Signalway Antibody

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产品详情

产品名称VEGF Conjugated Antibody

来源种属Rabbit

克隆性Monoclonal

应用IF, FC

种属反应性Hu, Ms, Rt

免疫原描述recombinant protein

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名Folliculostellate cell-derived growth factor antibody
Glioma-derived endothelial cell mitogen antibody
MGC70609 antibody
MVCD1 antibody
Vascular endothelial growth factor A antibody
vascular endothelial growth factor A121 antibody
vascular endothelial growth factor A165 antibody
vascular endothelial growth factor antibody
Vascular permeability factor antibody
VEGF A antibody
Vegf antibody
VEGF-A antibody
VEGF120 antibody
Vegfa antibody
VEGFA_HUMAN antibody
VPF antibody

数据库入口号Swiss-Prot#:P15692

计算分子量43 kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情

IF:1:50-1:200
FC: 1:50-1:200

背景

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factors (FGFs), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). VEGF is a dimeric glycoprotein with structural homology to PDGF. Several variants of VEGF have been described that arise by alternative mRNA splicing. It has been speculated that VEGF may function as a tumor angiogenesis factor in vivo because the expression pattern of VEGF is consistent with a role in embryonic angiogenesis. VEGF mRNA is formed in some primary tumors, VEGF is produced by tumor cell lines in vitro and VEGF mitogenic activity appears to be restricted to endothelial cells. A member of the PDGF receptor family, Flt, has been identified as a high-affinity receptor for VEGF.

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应用

WB免疫印迹
IHC免疫组化
IF免疫荧光
ICC免疫细胞化学
FC流式细胞
IP免疫沉淀
E酶联免疫吸附法
DB免疫斑点法
ChIP染色质免疫沉淀
GICA胶体金免疫层析法
NC阴性对照

种属反应性

Hu人
Ms小鼠
Rt大鼠
Dm果蝇
C线虫
Mk猴
Rb兔
B牛
D狗
P猪
Hm仓鼠
ChHm中国仓鼠
Chk鸡

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