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位置: 首页 > 标记抗体 > Olig2 Conjugated Antibody

Olig2 Conjugated Antibody#C48708

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称Olig2 Conjugated Antibody

来源种属Rabbit

克隆性Monoclonal

应用WB, IF

种属反应性Hu, Ms, Rt

免疫原描述recombinant protein

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名Basic domain helix loop helix protein class B 1 antibody
Basic helix loop helix protein class B 1 antibody
BHLHB antibody
bHLHB1 antibody
bHLHe19 antibody
Class B basic helix loop helix protein 1 antibody
Class B basic helix-loop-helix protein 1 antibody
class E basic helix loop helix protein 19 antibody
Class E basic helix-loop-helix protein 19 antibody
Human protein kinase C binding protein RACK17 antibody
Olig2 antibody
OLIG2_HUMAN antibody
Oligo2 antibody
Oligodendrocyte lineage transcription factor 2 antibody
Oligodendrocyte specific bHLH transcription factor 2 antibody
Oligodendrocyte transcription factor 2 antibody
OTTHUMP00000067569 antibody
OTTHUMP00000067570 antibody
PRKCBP2 antibody
Protein kinase C binding protein 2 antibody
Protein kinase C binding protein RACK17 antibody
Protein kinase C-binding protein 2 antibody
Protein kinase C-binding protein RACK17 antibody
RACK17 antibody

数据库入口号Swiss-Prot#:Q13516

计算分子量32 kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情
WB: 1:50-1:200
IF:1:50-1:200
背景
The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

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