CD86 Conjugated Antibody - SAB | Signalway Antibody

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产品名称CD86 Conjugated Antibody

来源种属Rabbit

克隆性Monoclonal

应用WB, IF, FC

种属反应性Hu Ms

免疫原描述recombinant protein

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名Activation B7-2 antigen 3 antibody
Activation B7-2 antigen antibody
B-lymphocyte activation antigen B7-2 2 antibody
B-lymphocyte activation antigen B7-2 antibody
B7 2 antibody
B7 antibody
B7-2 antibody
B7.2 antibody
B70 antibody
B72 antigen antibody
BU63 antibody
CD28 antigen ligand 2 2 antibody
CD28 antigen ligand 2 antibody
Cd28l2 antibody
CD28LG2 antibody
CD86 antibody
CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody
CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody
CD86 antigen antibody
CD86 molecule antibody
CD86_HUMAN antibody
CLS1 antibody
CTLA-4 counter-receptor B7.2 2, 3 antibody
CTLA-4 counter-receptor B7.2 antibody
Early T-cell costimulatory molecule 1 antibody
ETC-1 antibody
FUN 1 antibody
FUN-1 antibody
LAB72 antibody
Ly-58 antibody
Ly58 antibody
MB7 antibody
MB7-2 antibody
Membrane glycoprotein antibody
MGC34413 antibody
T-lymphocyte activation antigen CD86 antibody
TS/A-2 antibody

数据库入口号Swiss-Prot#:P42081

计算分子量70 kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情

WB: 1:50-1:200
IF:1:50-1:200
FC: 1:50-1:200

背景

T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins B7-1 (CD80) and B7-2 (CD86) expressed on antigen presenting cells bind the homologous T cell receptors CD28 and CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28, and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counterreceptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

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WB免疫印迹
IHC免疫组化
IF免疫荧光
ICC免疫细胞化学
FC流式细胞
IP免疫沉淀
E酶联免疫吸附法
DB免疫斑点法
ChIP染色质免疫沉淀
GICA胶体金免疫层析法
NC阴性对照

种属反应性

Hu人
Ms小鼠
Rt大鼠
Dm果蝇
C线虫
Mk猴
Rb兔
B牛
D狗
P猪
Hm仓鼠
ChHm中国仓鼠
Chk鸡

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CD86 Conjugated Antibody#C48763

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