免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 标记抗体 > JNK3 Conjugated Antibody

JNK3 Conjugated Antibody#C49181

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称JNK3 Conjugated Antibody

来源种属Rabbit

克隆性Monoclonal

应用WB, IF, FC

种属反应性Hu, Ms, Rt

免疫原描述recombinant protein

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名c Jun kinase 3 antibody
c-Jun N-terminal kinase 3 antibody
cJun N terminal kinase 3 antibody
FLJ12099 antibody
FLJ33785 antibody
JNK3 alpha protein kinase antibody
JNK3 antibody
JNK3A antibody
MAP kinase 10 antibody
MAP kinase antibody
MAP kinase p49 3F12 antibody
MAPK 10 antibody
Mapk10 antibody
MGC50974 antibody
mitogen activated protein kinase 10 antibody
Mitogen-activated protein kinase 10 antibody
MK10_HUMAN antibody
p493F12 antibody
p54bSAPK antibody
PRKM10 antibody
protein kinase mitogen activated 10 antibody
SAPK1b antibody
Stress activated protein kinase 1b antibody
stress activated protein kinase beta antibody
Stress activated protein kinase JNK3 antibody
Stress-activated protein kinase JNK3 antibody

数据库入口号Swiss-Prot#:P53779

计算分子量53 kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情
WB: 1:50-1:200
IF:1:50-1:200
FC: 1:50-1:200
背景
c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. JNK3 (MK10, MAPK10, PRKM10) is activated by pro-inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c-Jun and ATF2. This is important for AP-1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress-induced).

如果您使用该产品C49181发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com