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位置： 首页 > 标记抗体 > VPS26 Conjugated Antibody

VPS26 Conjugated Antibody#C49803

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产品详情

产品名称VPS26 Conjugated Antibody

来源种属Rabbit

克隆性Monoclonal

应用WB, IF

种属反应性Hu, Ms, Rt

免疫原描述Recombinant protein

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名FLJ12930 antibody
HB 58 antibody
HB58 antibody
Hbeta 58 antibody
Hbeta 58 homolog antibody
Hbeta58 antibody
Hbeta58 homolog antibody
hVPS 26 antibody
hVPS26 antibody
MGC94168 antibody
PEP 8A antibody
PEP8A antibody
Vacuolar protein sorting 26 A antibody
Vacuolar protein sorting 26 antibody
Vacuolar protein sorting 26 homolog A antibody
Vacuolar protein sorting 26 homolog A S. pombe antibody
Vacuolar protein sorting 26 homolog A yeast antibody
Vacuolar protein sorting 26 yeast antibody
Vacuolar protein sorting 26 yeast homolog antibody
Vacuolar protein sorting 26A antibody
Vacuolar protein sorting associated protein 26A antibody
Vacuolar protein sorting-associated protein 26A antibody
Vesicle protein sorting 26 antibody
Vesicle protein sorting 26A antibody
VP26A_HUMAN antibody
VPS 26 antibody
VPS 26A antibody
VPS26A antibody

数据库入口号Swiss-Prot#:O75436

计算分子量38 kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情
WB: 1:50-1:200
IF:1:50-1:200
背景
Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. Required for retrograde transport of lysosomal enzyme receptor IGF2R. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Required for the endosomal localization of WASHC2A (indicative for the WASH complex). Required for the endosomal localization of TBC1D5. Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP. Involved in retromer-independent lysosomal sorting of F2R. Involved in recycling of ADRB2. Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins.

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5

操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡

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Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com

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