产品详情
产品名称Anti-cancer Drug library
简述During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy, however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).
We carefully select 822 anticancer drugs including FDA approved and compounds in clinical trial phases as Anticancer Drug Library that can be used for tumor-related research and anti-tumor drug screening
保存Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
Shipped with dry ice
应用详情
Number of Compounds:822
产品描述
A unique collection of 822 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
Bioactivity and safety profiled in (confirmed by) pre-clinical and clinical settings (research and trials), an effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug repositioning drug discovery;
Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc; involved in 15 different cancer research areas, such as lung cancer, breast cancer, leukemia, lymphoma, etc.
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality
Yes
