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DBI Polyclonal Antibody#30286

DBI Polyclonal Antibody
DBI Polyclonal Antibody
DBI Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称DBI Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC,IF

种属反应性Human,Mouse,Rat

免疫原描述Recombinant fusion protein of human DBI (NP_001171513.1).

别名DBI; ACBD1; ACBP; CCK-RP; EP; acyl-CoA-binding protein

数据库入口号Swiss-Prot#:P07108
NCBI Gene ID:1622

计算分子量10kDa

配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

保存Store at -20˚C

应用详情
WB 1:1000 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using AREG antibody at 1:3000 dilution.
Immunohistochemistry of paraffin-embedded human liver using AREG antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human tonsil using AREG antibody at dilution of 1:100 (40x lens).
背景
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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